Our Mission
The mission of DSRTF is to stimulate biomedical research that will accelerate the development of treatments to significantly improve cognition for individuals with Down syndrome.
Learn More.
Now Is the Time To Energize DS Research
The recent mapping of the human genome has ushered in an unprecedented opportunity for Down syndrome research. For the first time in our history scientists now have tools, techniques, and mouse models of DS that are making it easier to understand the biology of Down syndrome. The goal is clear – the identification of treatments aimed at improving learning, memory, speech
and even the late in life neurological decline experienced by those with Down
syndrome.
A Small Change in Cognitive Capability Could Have Profound Impact on Independence
Because the majority of individuals with Down syndrome fall into the mild to moderate range of cognitive impairment, a 10-20% improvement in cognitive capability can provide a greater number of people with the ability to live independently, to hold a job and to be more integrated into their communities.
 |
|
DSRTF Awards New Innovation Research Grant for more than $110,000 to Drs. Lynn Nadel and Jamie Edgin, University of Arizona:
The Down Syndrome Research and Treatment Foundation (DSRTF) has announced the award and funding for a new Innovation Research Grant, totaling $113,719, to Lynn Nadel, Ph.D., Regent’s Professor, and Jamie Edgin, Ph.D., Research Associate, in the Department of Psychology, University of Arizona. This new DSRTF Innovation Research Grant will allow Drs. Nadel and Edgin to further define the considerable heterogeneity in cognitive outcomes in Down syndrome. Their long-term goal is to uncover the factors that lead to variation in the cognitive characteristics (phenotype) of Down syndrome. In examining the factors relating to variation in cognitive function, they focus on the function of three specific brain regions, the hippocampus, prefrontal cortex and cerebellum. They believe these brain systems are central to the cognitive difficulties experienced by those with Down syndrome, because they are critical to everyday tasks such as attention, decision-making, and memory.
Learn More.
DSRTF Awards New $880,000 Research Center Grant to Stanford School of Medicine Researchers:
The Down Syndrome Research and Treatment Foundation (DSRTF) is pleased to announce the award and funding for a major new $880,000 DSRTF Research Center Grant to researchers at the Center for Research and Treatment of Down Syndrome and Neuroscience Institute at the Stanford University School of Medicine.
Learn More.
Genetic Role Discovered for Lower Incidence of Solid Tumor Cancers in Down Syndrome:
New research conducted by DSRTF Scientific Advisory Board member Dr. Roger Reeves, Professor at Johns Hopkins School of Medicine, and his colleagues has led to the discovery that increased levels of a chromosome 21 gene, designated Ets2, result in significantly lower incidence, and smaller size, of intestinal tumors in DS mouse models.
Learn More.
DSRTF Awards New $250,000 Research Grant to Dr. Roger Reeves, Johns Hopkins School of Medicine, for Novel Potential Therapeutic Target to
Address Cognitive Impairment in Down Syndrome:
The Down Syndrome Research and Treatment Foundation (DSRTF) has announced the award and funding for a major new DSRTF Research Grant to Roger H. Reeves, Ph.D., Professor, Department of Physiology and McKusick-Nathans Institute for Genetic Medicine at Johns Hopkins School of Medicine, to significantly extend research concerning a novel potential therapeutic target involving neurogenesis (nerve cell development) to ameliorate cognitive impairment in Down syndrome. This new grant represents the latest DSRTF research initiative as part of the targeted expansion of the Foundation's strategy to stimulate and facilitate the most promising biomedical research that will accelerate development of treatments to significantly improve cognition, including memory, learning and speech, for children and adults with Down syndrome.
Learn More.
DSRTF funded researchers see promise in PTZ:
Lab mice with the mental retardation of Down syndrome got smarter after being fed a drug that strengthened brain circuits involved in learning and memory.
Learn more.
|
Events & Fundraisers:
Empower your online purchases to support DS Research!
New York Area Romp for Research- September 14, 2008
An Evening with Danny Aiello- September 17, 2008- E. Rutherford, NJ
7th Annual DSRTF Massachusetts Charity Golf Tournament- September 21, 2008
Alexander's Angels 2nd Annual Long Island Buddy Walk- October 4, 2008
One EXtra Reason to Live, Love, Hope- October 11, 2008- Hollywood, CA
The Cruise with a Cause-
June 5, 2009-June 8, 2009
|
